LASER server: ancestry tracing with genotypes or sequence reads

نویسندگان

  • Daniel Taliun
  • Sonia P. Chothani
  • Sebastian Schönherr
  • Lukas Forer
  • Michael Boehnke
  • Gonçalo R. Abecasis
  • Chaolong Wang
چکیده

Summary To enable direct comparison of ancestry background in different studies, we developed LASER to estimate individual ancestry by placing either sezquenced or genotyped samples in a common ancestry space, regardless of the sequencing strategy or genotyping array used to characterize each sample. Here we describe the LASER server to facilitate application of the method to a wide range of genetic studies. The server provides genetic ancestry estimation for different geographic regions and user-friendly interactive visualization of the results. Availability and Implementation The LASER server is freely accessible at http://laser.sph.umich.edu/. Contact [email protected] or [email protected]. Supplementary information Supplementary data are available at Bioinformatics online.

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عنوان ژورنال:

دوره 33  شماره 

صفحات  -

تاریخ انتشار 2017